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In the Middle Ages, women with freckles or any kind of beauty spots were laughed at, but oh, how things have changed!

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Models with freckles may be concerned that opportunities in the industry may be slim. However, the reality is very different with the facial markings to be viewed as a of beauty and featuring the freckled faces on the front of fashion and beauty campaigns. The modelling industry is slowly becoming a diverse place that accepts a variety of skin tones and complexions and therefore, models with freckles are included within the new approach. Freckles compliment auburn or brown hair beautifully and the coverage varies depending on the person. Yet it is encouraging to witness different skin types within the fashion industry arena and for individuals to passionately campaign for a change to happen.

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Freckles or ephelides are hyperpigmented spots observed on skin surface mainly in European and Asian populations.

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Easy recognition and external visibility make prediction of ephelides, the potentially useful target in the field of forensic DNA phenotyping. Prediction of freckles would be a step forward in sketching the physical appearance of unknown perpetrators or decomposed cadavers for the forensic DNA intelligence purposes.

Freckles are especially common in people with pale skin and red hair and therefore it is expected that predisposition to freckles may partially share the genetic background with other pigmentation traits.

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The first proposed freckle prediction model was developed based on investigation that involved variation of MC1R and 8 SNPs from 7 genes in a Spanish cohort [ 19 ]. In this study we examined DNA variants from 46 genes ly associated with human pigmentation traits and assessed their impact on freckles presence in a group of individuals from Poland.

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Two alternative prediction models were developed using regression methods. A multinomial variable model predicts one of three — non-freckled, medium freckled and heavily freckled.

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The study presents novel DNA models for prediction of freckles that can be used in forensic investigations and emphasizes ificance of pigmentation genes and sex in predictive DNA analysis of freckles. View PDF Download full issue.

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Abstract Freckles or ephelides are hyperpigmented spots observed on skin surface mainly in European and Asian populations. Keywords Freckles.

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Recommended articles Citing articles 0. Published by Elsevier B.

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